BMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion

The exocrine pancreas can give rise to endocrine insulin-producing cells upon ectopic expression of key transcription factors. However, the need for genetic manipulation remains a translational hurdle for diabetes therapy. Here we report the conversion of adult human nonendocrine pancreatic tissue i...

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Vydáno v:Diabetes
Hlavní autoři: Klein, Dagmar, Álvarez-Cubela, Silvia, Lanzoni, Giacomo, Vargas, Nancy, Prabakar, Kamalaveni R., Boulina, Maria, Ricordi, Camillo, Inverardi, Luca, Pastori, Ricardo L., Domínguez-Bendala, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
Islet Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657585/
https://ncbi.nlm.nih.gov/pubmed/26307584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0688
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