Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials

Clinically relevant weight loss is achievable through lifestyle modification, but unintentional weight regain is common. We investigated whether recently discovered genetic variants affect weight loss and/or weight regain during behavioral intervention. Participants at high-risk of type 2 diabetes (...

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Vydáno v:Diabetes
Hlavní autoři: Papandonatos, George D., Pan, Qing, Pajewski, Nicholas M., Delahanty, Linda M., Peter, Inga, Erar, Bahar, Ahmad, Shafqat, Harden, Maegan, Chen, Ling, Fontanillas, Pierre, Wagenknecht, Lynne E., Kahn, Steven E., Wing, Rena R., Jablonski, Kathleen A., Huggins, Gordon S., Knowler, William C., Florez, Jose C., McCaffery, Jeanne M., Franks, Paul W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
Genetics/Genomes/Proteomics/Metabolomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657576/
https://ncbi.nlm.nih.gov/pubmed/26253612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0441
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