Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome

BACKGROUND: Williams-Beuren Syndrome (WBS) is caused by the microdeletion of approximately 25 genes on chromosome 7q11.23, and is characterized by a spectrum of cognitive and behavioural features. RESULTS: We generated cortical neurons from a WBS individual and unaffected (WT) control by directed di...

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Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Khattak, Shahryar, Brimble, Elise, Zhang, Wenbo, Zaslavsky, Kirill, Strong, Emma, Ross, P. Joel, Hendry, Jason, Mital, Seema, Salter, Michael W., Osborne, Lucy R., Ellis, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657290/
https://ncbi.nlm.nih.gov/pubmed/26603386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0168-0
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