Glucocorticoid receptor antagonism reverts docetaxel resistance in human prostate cancer

Resistance to docetaxel is a major clinical problem in advanced prostate cancer (PCa). Although glucocorticoids (GCs) are frequently used in combination with docetaxel, it is unclear to what extent GCs and their receptor, the glucocorticoid receptor (GR), contribute to the chemotherapy resistance. I...

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Bibliografiska uppgifter
I publikationen:Endocr Relat Cancer
Huvudupphovsmän: Kroon, Jan, Puhr, Martin, Buijs, Jeroen T, van der Horst, Geertje, Hemmer, Daniëlle M, Marijt, Koen A, Hwang, Ming S, Masood, Motasim, Grimm, Stefan, Storm, Gert, Metselaar, Josbert M, Meijer, Onno C, Culig, Zoran, van der Pluijm, Gabri
Materialtyp: Artigo
Språk:Inglês
Publicerad: Bioscientifica Ltd 2016
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657186/
https://ncbi.nlm.nih.gov/pubmed/26483423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-15-0343
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