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The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is abundantly expressed in trained muscles and regulates muscle adaptation to endurance exercise. Inversely, mice lacking a functional PGC-1α allele in muscle exhibit reduced muscle functionality and increased inflammation. In...
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| 發表在: | Biochem Biophys Res Commun |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657152/ https://ncbi.nlm.nih.gov/pubmed/26159922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.06.166 |
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