Non-invasive Bioluminescence Imaging of Myoblast-Mediated Hypoxia-Inducible Factor-1 Alpha Gene Transfer

PURPOSE: We tested a novel imaging strategy, in which both the survival of transplanted myoblasts and their therapeutic transgene expression, a recombinant hypoxia-inducible factor-1α (HIF-1α-VP2), can be monitored using firefly luciferase (fluc) and Renilla luciferase (hrl) bioluminescence reporter...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Gheysens, Olivier, Chen, Ian Y., Rodriguez-Porcel, Martin, Chan, Carmel, Rasooly, Julia, Vaerenberg, Caroline, Paulmurugan, Ramasamy, Willmann, Juergen K., Deroose, Christophe, Wu, Joseph, Gambhir, Sanjiv S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657136/
https://ncbi.nlm.nih.gov/pubmed/21267661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0471-9
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