Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy

Reverse transcriptase (RT) mutations contribute to hepatitis B virus resistance during antiviral therapy with nucleos(t)ide analogs. However, the composition of the RT quasispecies and their interactions during antiviral treatment have not yet been thoroughly defined. In this report, 10 patients fro...

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Vydáno v:Sci Rep
Hlavní autoři: Zhou, Bin, Dong, Hui, He, Yungang, Sun, Jian, Jin, Weirong, Xie, Qing, Fan, Rong, Wang, Minxian, Li, Ran, Chen, Yangyi, Xie, Shaoqing, Shen, Yan, Huang, Xin, Wang, Shengyue, Lu, Fengming, Jia, Jidong, Zhuang, Hui, Locarnini, Stephen, Zhao, Guo-Ping, Jin, Li, Hou, Jinlin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657086/
https://ncbi.nlm.nih.gov/pubmed/26599443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17123
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