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First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90

The involvement of Hsp90 in progression of diseases like cancer, neurological disorders and several pathogen related conditions is well established. Hsp90, therefore, has emerged as an attractive drug target for many of these diseases. Several small molecule inhibitors of Hsp90, such as geldanamycin...

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Publicat a:Sci Rep
Autors principals: Raman, Swetha, Singh, Meetali, Tatu, Utpal, Suguna, Kaza
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657054/
https://ncbi.nlm.nih.gov/pubmed/26599366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17015
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