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First Structural View of a Peptide Interacting with the Nucleotide Binding Domain of Heat Shock Protein 90

The involvement of Hsp90 in progression of diseases like cancer, neurological disorders and several pathogen related conditions is well established. Hsp90, therefore, has emerged as an attractive drug target for many of these diseases. Several small molecule inhibitors of Hsp90, such as geldanamycin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Raman, Swetha, Singh, Meetali, Tatu, Utpal, Suguna, Kaza
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657054/
https://ncbi.nlm.nih.gov/pubmed/26599366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17015
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