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RNA-based, transient modulation of gene expression in human haematopoietic stem and progenitor cells

Modulation of gene expression is a useful tool to study the biology of haematopoietic stem and progenitor cells (HSPCs) and might also be instrumental to expand these cells for therapeutic approaches. Most of the studies so far have employed stable gene modification by viral vectors that are burdens...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Diener, Yvonne, Jurk, Marion, Kandil, Britta, Choi, Yeong-Hoon, Wild, Stefan, Bissels, Ute, Bosio, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657003/
https://ncbi.nlm.nih.gov/pubmed/26599627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17184
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