The Molecular Mechanism Underlying Recruitment and Insertion of Lipid-Anchored LC3 Protein into Membranes

Lipid modification of cytoplasmic proteins initiates membrane engagement that triggers diverse cellular processes. Despite the abundance of lipidated proteins in the human proteome, the key determinants underlying membrane recognition and insertion are poorly understood. Here, we define the course o...

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Udgivet i:Biophys J
Main Authors: Thukral, Lipi, Sengupta, Durba, Ramkumar, Amrita, Murthy, Divya, Agrawal, Nikhil, Gokhale, Rajesh S.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Membranes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656858/
https://ncbi.nlm.nih.gov/pubmed/26588566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.09.022
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