Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes

Oxidative stress plays an important role in doxorubicin (DOX)-induced cardiotoxicity. Nuclear factor E2-related factor-2 (Nrf2) is a transcription factor that orchestrates the antioxidant and cytoprotective responses to oxidative stress. In the present study, we tested whether tert-butylhydroquinone...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Wang, Lin-Feng, Su, Su-Wen, Wang, Lei, Zhang, Guo-Qiang, Zhang, Rong, Niu, Yu-Jie, Guo, Yan-Su, Li, Chun-Yan, Jiang, Wen-Bo, Liu, Yi, Guo, Hui-Cai
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656753/
https://ncbi.nlm.nih.gov/pubmed/26692920
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