MicroRNA-212 functions as an epigenetic-silenced tumor suppressor involving in tumor metastasis and invasion of gastric cancer through down-regulating PXN expression

Altered expression of paxillin (PXN) is closely linked to the pathogenesis progression, metastasis and prognosis of different malignancies including gastric cancer (GC). Epigenetic silencing of tumor-suppressive microRNAs (miRNAs) is a crucial component of the mechanism underlying activation of onco...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Li, Daojiang, Li, Zhengrong, Xiong, Jianbo, Gong, Binbin, Zhang, Guoyang, Cao, Chao, Jie, Zhigang, Liu, Yi, Cao, Yi, Yan, Yufeng, Xiong, Hong, Qiu, Lingyu, Yang, Miantian, Chen, Hongping, Jiang, Shuping, Yang, Xiongwen, Chen, Heping
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656725/
https://ncbi.nlm.nih.gov/pubmed/26693054
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