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Single-molecule imaging reveals a switch between spurious and functional ncRNA transcription

Eukaryotic transcription is pervasive, and many of the resulting RNAs are non-coding. It is unknown if ubiquitous transcription is functional or simply reflects stochastic transcriptional noise. By single-molecule visualization of the dynamic interplay between coding and non-coding transcription at...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Lenstra, Tineke L., Coulon, Antoine, Chow, Carson C., Larson, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656089/
https://ncbi.nlm.nih.gov/pubmed/26549684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.028
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