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Notch Signaling and M1 Macrophage Activation in Obesity-alcohol Synergism

Macrophages are a key cell type in the innate immune system, and its proinflammatory (M1) activation in the liver plays a critical role in pathogenesis of alcoholic steatohepatitis. Emerging evidence indicates the involvement of Notch signaling in regulation of innate immune response and cellular me...

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Publicado en:Clin Res Hepatol Gastroenterol
Autores principales: Xu, Jun, Chi, Feng, Tsukamoto, Hidekazu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656026/
https://ncbi.nlm.nih.gov/pubmed/26189984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinre.2015.05.016
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