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Combination of PEI-Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma

BACKGROUND: To explore a new combination of thermal treatment and gene therapy for hepatoma, a heat-inducible herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) gene therapy system was developed in which thermal energy generated by Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles (MZF-NPs) under an...

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Publicat a:Int J Nanomedicine
Autors principals: Tang, Qiusha, Lu, Mudan, Chen, Daozhen, Liu, Peidang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655962/
https://ncbi.nlm.nih.gov/pubmed/26604760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S92179
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