Nemo-like kinase (NLK) negatively regulates NF-kappa B activity through disrupting the interaction of TAK1 with IKKβ

Stringent negative regulation of the transcription factor NF-κB is essential for maintaining cellular stress responses and homeostasis. However, the tight regulation mechanisms of IKKβ are still not clear. Here, we reported that nemo-like kinase (NLK) is a suppressor of tumor necrosis factor (TNFα)-...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Li, Shang-Ze, Zhang, Hui-Hui, Liang, Jun-Bo, Song, Yang, Jin, Bing-Xue, Xing, Na-Na, Fan, Guo-Chang, Du, Run-Lei, Zhang, Xiao-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655877/
https://ncbi.nlm.nih.gov/pubmed/24721172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.03.028
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