Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

The endothelial lining of blood vessels is constantly exposed to fluid mechanical forces generated by flowing blood. In vitro application of fluid shear stresses to cultured endothelial cells influences the expression of multiple genes, as reflected by changes in their steady-state mRNA levels. We h...

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Bibliographic Details
Main Authors: Resnick, N, Collins, T, Atkinson, W, Bonthron, D T, Dewey, C F, Gimbrone, M A
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC46558/
https://ncbi.nlm.nih.gov/pubmed/8506304
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