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The costimulatory activity of the CD26 antigen requires dipeptidyl peptidase IV enzymatic activity.

T cells have been shown to express CD26, a known ectoenzyme with dipeptidyl peptidase IV (DPPIV; EC 3.4.14.5) activity in its extracellular domain. CD26 can also deliver a second costimulatory signal and contribute to T-cell activation. In an earlier study, we established CD26-transfected Jurkat T-c...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tanaka, T, Kameoka, J, Yaron, A, Schlossman, S F, Morimoto, C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7685106/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4586
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