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Synthesis of [(18)F] 4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide (IDO5L): a novel potential PET probe for imaging of IDO1 expression

To synthesize (18)F-labeled positron emission tomography (PET) ligands, reliable labeling techniques inserting (18)F into a target molecule are necessary. The (18)F-fluorobenzene moiety has been widely utilized in the synthesis of (18)F-labeled compounds. The present study utilized [(18)F]-labeled a...

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Pubblicato in:J Labelled Comp Radiopharm
Autori principali: Huang, Xuan, Gillies, Robert J., Tian, Haibin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655588/
https://ncbi.nlm.nih.gov/pubmed/25690452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3263
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