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An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice

Activation of complement is a key determinant of neuropathology and disability after traumatic brain injury (TBI), and inhibition is neuroprotective. However, systemic complement is essential to fight infections, a critical complication of TBI. We describe a targeted complement inhibitor, comprising...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Ruseva, Marieta M., Ramaglia, Valeria, Morgan, B. Paul, Harris, Claire L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655525/
https://ncbi.nlm.nih.gov/pubmed/26578778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513698112
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