Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

BACKGROUND: This study aimed to investigate whether the DNA methylation of human ovarian carcinoma stromal progenitor cells (OCSPCs) could promote the tumorigenesis of ovarian carcinoma. METHODS: OCSPCs were first isolated from fresh tumor tissues and ascites of ovarian cancer patients. In vivo and...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ho, Chih-Ming, Shih, Daniel Tzu-bi, Hsiao, Chih-Chiang, Huang, Shih-Hung, Chang, Shwu-Fen, Cheng, Wen-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655458/
https://ncbi.nlm.nih.gov/pubmed/26597084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0722-7
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