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Engraftment of human induced pluripotent stem cell-derived hepatocytes in immunocompetent mice via 3D co-aggregation and encapsulation

Cellular therapies for liver diseases and in vitro models for drug testing both require functional human hepatocytes (Hum-H), which have unfortunately been limited due to the paucity of donor liver tissues. Human pluripotent stem cells (hPSCs) represent a promising and potentially unlimited cell sou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Wei, Lu, Yen-Chun, Frankel, Angela S., An, Duo, Schwartz, Robert E., Ma, Minglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655358/
https://ncbi.nlm.nih.gov/pubmed/26592180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16884
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