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Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain

Failure to close the neural tube results in birth defects, with severity ranging from spina bifida to lethal anencephaly. Few genetic risk factors for neural tube defects are known in humans, highlighting the critical role of environmental risk factors, such as maternal diabetes. Yet, it is not well...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Salbaum, J. Michael, Kruger, Claudia, MacGowan, Jacalyn, Herion, Nils J., Burk, David, Kappen, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655353/
https://ncbi.nlm.nih.gov/pubmed/26593875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16917
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