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CD8 T cells enter the splenic T cell zones independently of CCR7 but the subsequent expansion and trafficking patterns of effector T cells after infection are dysregulated in the absence of CCR7 migratory cues()
CCR7 is an important chemokine receptor which regulates T cell trafficking and compartmentalization within secondary lymphoid organs. However, the T cell intrinsic role of CCR7 during infection in the spleen is not well understood. This study was designed to understand how CCR7 dependent localizatio...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655190/ https://ncbi.nlm.nih.gov/pubmed/26500349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500993 |
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