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A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels

BACKGROUND: A deeper understanding of differences and similarities in transcriptional regulation between species can uncover important information about gene functions and the role of genes in disease. Deciphering such patterns between mice and humans is especially important since mice play an essen...

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Détails bibliographiques
Publié dans:BMC Evol Biol
Auteurs principaux: Monaco, Gianni, van Dam, Sipko, Casal Novo Ribeiro, João Luis, Larbi, Anis, de Magalhães, João Pedro
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654840/
https://ncbi.nlm.nih.gov/pubmed/26589719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0534-7
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