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Highly-Efficient and Versatile Fluorous-Tagged Cu(I)-Catalyzed Azide-Alkyne Cycloaddition Ligand for Preparing Bioconjugates

A novel ligand (FBTTBE) for Cu(I)-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) has been developed, which demonstrates not only superior catalytic efficiency but also the ease of removing toxic copper species. FBTTBE has also been successfully applied in the synthesis of radiometal-labeled peptide an...

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Publicat a:Chem Commun (Camb)
Autors principals: Sun, Lingyi, Gai, Yongkang, Anderson, Carolyn J., Zeng, Dexing
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654650/
https://ncbi.nlm.nih.gov/pubmed/26426419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc06858d
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