Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis

Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the signalling pathways mediating tolerogenic DC function in vivo remain largely unknown. The β-catenin pathway has been suggested to promote a regulatory...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Alves, C. Henrique, Ober-Blöbaum, Julia L., Brouwers-Haspels, Inge, Asmawidjaja, Patrick S., Mus, Adriana M. C., Razawy, Wida, Molendijk, Marlieke, Clausen, Björn E., Lubberts, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654567/
https://ncbi.nlm.nih.gov/pubmed/26587585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142972
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