Characterization of FGF23-Dependent Egr-1 Cistrome in the Mouse Renal Proximal Tubule

Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphate (Pi) and vitamin D homeostasis. The transcription factor, early growth response 1 (egr-1), is a biomarker for FGF23-induced activation of the ERK1/2 signaling pathway. We have shown that ERK1/2 signaling blockade suppresses renal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Portale, Anthony A., Zhang, Martin Y. H., David, Valentin, Martin, Aline, Jiao, Yan, Gu, Weikuan, Perwad, Farzana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654537/
https://ncbi.nlm.nih.gov/pubmed/26588476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142924
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