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Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major

Leishmania major (L. major) is a protozoan parasite causal agent of Leishmaniasis. It is estimated that 12 million people are currently infected and around 2 million infections occur each year. Current treatments suffer of high toxicity for the patient, low efficacy toward the parasite, high cost, a...

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Vydáno v:Bioorg Med Chem Lett
Hlavní autoři: Iniguez, Eva A., Perez, Andrea, Maldonado, Rosa A., Skouta, Rachid
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654408/
https://ncbi.nlm.nih.gov/pubmed/26410073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.09.041
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