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Discovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytes

Plasmodium falciparum virulence is linked to its ability to sequester in post-capillary venules in the human host. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is the main variant surface antigen implicated in this process. Complete loss of parasite adhesion is linked to a large sub...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Nacer, Adéla, Claes, Aurélie, Roberts, Amy, Scheidig-Benatar, Christine, Sakamoto, Hiroshi, Ghorbal, Mehdi, Lopez-Rubio, Jose-Juan, Mattei, Denise
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654329/
https://ncbi.nlm.nih.gov/pubmed/25703704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12430
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