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Relationship between interleukin-1 type 1 and 2 receptor gene polymorphisms and the expression level of membrane-bound receptors

The biological activity of the multifunctional cytokine interleukin-1 (IL-1) is mediated by its receptors. The aim of this study was to determine if an association exists between single nucleotide polymorphisms (SNPs) in the IL-1 type 1 and 2 receptor genes (IL1R1 and IL1R2) and the expression level...

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Pubblicato in:Cell Mol Immunol
Autori principali: Vasilyev, FF, Silkov, AN, Sennikov, SV
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654293/
https://ncbi.nlm.nih.gov/pubmed/24976267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.43
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