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A neural crest origin for cohesinopathy heart defects

Mutations in subunits or regulators of cohesin cause a spectrum of disorders in humans known as the ‘cohesinopathies’. Cohesinopathies, including the best known example Cornelia de Lange syndrome (CdLS), are characterized by broad spectrum, multifactorial developmental anomalies. Heart defects occur...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Schuster, Kevin, Leeke, Bryony, Meier, Michael, Wang, Yizhou, Newman, Trent, Burgess, Sean, Horsfield, Julia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654055/
https://ncbi.nlm.nih.gov/pubmed/26420840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv402
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