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Understanding the contrasting spatial haplotype patterns of malaria-protective β-globin polymorphisms
The malaria-protective β-globin polymorphisms, sickle-cell (β(S)) and β(0)-thalassaemia, are canonical examples of human adaptation to infectious disease. Occurring on distinct genetic backgrounds, they vary markedly in their patterns of linked genetic variation at the population level, suggesting d...
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| Publicado no: | Infect Genet Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653953/ https://ncbi.nlm.nih.gov/pubmed/26394108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2015.09.018 |
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