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Folding of newly translated membrane protein CCR5 is assisted by the chaperonin GroEL-GroES

The in vitro folding of newly translated human CC chemokine receptor type 5 (CCR5), which belongs to the physiologically important family of G protein-coupled receptors (GPCRs), has been studied in a cell-free system supplemented with the surfactant Brij-35. The freshly synthesized CCR5 can spontane...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Chi, Haixia, Wang, Xiaoqiang, Li, Jiqiang, Ren, Hao, Huang, Fang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653635/
https://ncbi.nlm.nih.gov/pubmed/26585937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17037
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