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Folding of newly translated membrane protein CCR5 is assisted by the chaperonin GroEL-GroES
The in vitro folding of newly translated human CC chemokine receptor type 5 (CCR5), which belongs to the physiologically important family of G protein-coupled receptors (GPCRs), has been studied in a cell-free system supplemented with the surfactant Brij-35. The freshly synthesized CCR5 can spontane...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653635/ https://ncbi.nlm.nih.gov/pubmed/26585937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17037 |
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