Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis.
The interaction of tumor necrosis factor alpha (TNF) with its two membrane-bound receptors initiates intracellular events in which arachidonic acid and its derivatives are involved. In HeLa cells, TNF treatment induces an arachidonic acid-selective, Ca(2+)-dependent cellular phospholipase A2 (cPLA2)...
Furkejuvvon:
| Publikašuvnnas: | Proc Natl Acad Sci U S A |
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| Váldodahkkit: | , , , , |
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
National Academy of Sciences
1993
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| Fáttát: | |
| Liŋkkat: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4475 |
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