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A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA)
Motivation: We address the following question: Does inhibition of the expression of a gene X in a cellular assay affect the expression of another gene Y? Rather than inhibiting gene X experimentally, we aim at answering this question computationally using as the only input observational gene express...
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Publicado no: | Bioinformatics |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653390/ https://ncbi.nlm.nih.gov/pubmed/26249813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv461 |
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