Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling

BACKGROUND: Trauma often cooccurs with cardiac arrest and hemorrhagic shock. Skin and muscle injuries often lead to significant inflammation in the affected tissue. The primary mechanism by which inflammation is initiated, sustained, and terminated is cytokine-mediated immune signaling, but this sig...

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Publicat a:Front Immunol
Autors principals: Starzl, Ravi, Wolfram, Dolores, Zamora, Ruben, Jefferson, Bahiyyah, Barclay, Derek, Ho, Chien, Gorantla, Vijay, Brandacher, Gerald, Schneeberger, Stefan, Andrew Lee, W. P., Carbonell, Jaime, Vodovotz, Yoram
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653302/
https://ncbi.nlm.nih.gov/pubmed/26635801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00587
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