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RNAIII of the Staphylococcus aureus agr system activates global regulator MgrA by stabilizing mRNA

RNAIII, the effector of the agr quorum-sensing system, plays a key role in virulence gene regulation in Staphylococcus aureus, but how RNAIII transcriptionally regulates its downstream genes is not completely understood. Here, we show that RNAIII stabilizes mgrA mRNA, thereby increasing the producti...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gupta, Ravi Kr., Luong, Thanh T., Lee, Chia Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653210/
https://ncbi.nlm.nih.gov/pubmed/26504242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509251112
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