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Extrathymic differentiation of T lymphocytes and natural killer cells from human embryonic liver precursors.

Liver cells were isolated on Ficoll/Hypaque gradients from embryos or fetuses at 6-10 weeks of gestation; 2-20% of the cells expressed CD45 or HLA class I surface antigens and 2-6% expressed CD7. Other T- or natural-killer (NK)-cell-lineage-specific markers were undetectable. Liver-cell suspensions...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Poggi, A, Sargiacomo, M, Biassoni, R, Pella, N, Sivori, S, Revello, V, Costa, P, Valtieri, M, Russo, G, Mingari, M C
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4465
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