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Defining the mRNA recognition signature of a bacterial toxin protein

Bacteria contain multiple type II toxins that selectively degrade mRNAs bound to the ribosome to regulate translation and growth and facilitate survival during the stringent response. Ribosome-dependent toxins recognize a variety of three-nucleotide codons within the aminoacyl (A) site, but how thes...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Schureck, Marc A., Dunkle, Jack A., Maehigashi, Tatsuya, Miles, Stacey J., Dunham, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653167/
https://ncbi.nlm.nih.gov/pubmed/26508639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512959112
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