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Endocannabinoid signaling mediates oxytocin-driven social reward

Marijuana exerts profound effects on human social behavior, but the neural substrates underlying such effects are unknown. Here we report that social contact increases, whereas isolation decreases, the mobilization of the endogenous marijuana-like neurotransmitter, anandamide, in the mouse nucleus a...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wei, Don, Lee, DaYeon, Cox, Conor D., Karsten, Carley A., Peñagarikano, Olga, Geschwind, Daniel H., Gall, Christine M., Piomelli, Daniele
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653148/
https://ncbi.nlm.nih.gov/pubmed/26504214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509795112
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