Anti-inflammatory properties of mutolide isolated from the fungus Lepidosphaeria species (PM0651419)

Mutolide an anti-inflammatory compound was isolated from the coprophilous fungus Lepidosphaeria sp. (PM0651419). The compound mitigated LPS-induced secretion of pro-inflammatory cytokines TNF-α and IL-6 from THP-1 cells as well as human peripheral blood mononuclear cells (hPBMCs). Mutolide also inhi...

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Publicado en:Springerplus
Main Authors: Shah, Meet, Deshmukh, Sunil Kumar, Verekar, Shilpa A., Gohil, Akash, Kate, Abhijeet S., Rekha, V., Kulkarni-Almeida, Asha
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653127/
https://ncbi.nlm.nih.gov/pubmed/26618095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1493-6
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