Enteric nervous system α-synuclein immunoreactivity in idiopathic REM sleep behavior disorder

OBJECTIVE: To investigate the expression of α-synuclein in colonic biopsies of patients with idiopathic REM sleep behavior disorder (iRBD) and address if α-synuclein immunostaining of tissue obtained via colonic biopsies holds promise as a diagnostic biomarker for prodromal Parkinson disease (PD). M...

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Détails bibliographiques
Publié dans:Neurology
Auteurs principaux: Sprenger, Fabienne S., Stefanova, Nadia, Gelpi, Ellen, Seppi, Klaus, Navarro-Otano, Judith, Offner, Felix, Vilas, Dolores, Valldeoriola, Francesc, Pont-Sunyer, Claustre, Aldecoa, Iban, Gaig, Carles, Gines, Angels, Cuatrecasas, Miriam, Högl, Birgit, Frauscher, Birgit, Iranzo, Alex, Wenning, Gregor K., Vogel, Wolfgang, Tolosa, Eduardo, Poewe, Werner
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653104/
https://ncbi.nlm.nih.gov/pubmed/26475692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002126
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