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Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo

Myocyte enhancer factor (Mef)-2 transcription factors are implicated in activity-dependent neuronal processes during development, but the role of MEF2 in neural stem/progenitor cells (NSPCs) in the adult brain is unknown. We used a transgenic mouse in which Mef2a, -c, and -d were inducibly deleted i...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Latchney, Sarah E., Jiang, Yindi, Petrik, David P., Eisch, Amelia J., Hsieh, Jenny
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653059/
https://ncbi.nlm.nih.gov/pubmed/26286136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275651
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