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Inhibition of Wnt/β-catenin pathway promotes regenerative repair of cutaneous and cartilage injury
Wound healing in mammals is a fibrotic process. The mechanisms driving fibrotic (as opposed to regenerative) repair are poorly understood. Herein we report that therapeutic Wnt inhibition with topical application of small-molecule Wnt inhibitors can reduce fibrosis and promote regenerative cutaneous...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653050/ https://ncbi.nlm.nih.gov/pubmed/26268926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275941 |
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