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Mass cytometric functional profiling of acute myeloid leukemia defines cell cycle and immunophenotypic properties that correlate with known responses to therapy

Acute myeloid leukemia (AML) is characterized by a high relapse rate that has been attributed to the quiescence of leukemia stem cells (LSCs), which renders them resistant to chemotherapy. However, this hypothesis is largely supported by indirect evidence and fails to explain the large differences i...

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Detaylı Bibliyografya
Yayımlandı:Cancer Discov
Asıl Yazarlar: Behbehani, Gregory K., Samusik, Nikolay, Bjornson, Zach B., Fantl, Wendy J., Medeiros, Bruno C., Nolan, Garry P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652947/
https://ncbi.nlm.nih.gov/pubmed/26091827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0298
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