Novel insights into RNP granules by employing the trypanosome's microtubule skeleton as a molecular sieve

RNP granules are ribonucleoprotein assemblies that regulate the post-transcriptional fate of mRNAs in all eukaryotes. Their exact function remains poorly understood, one reason for this is that RNP granule purification has not yet been achieved. We have exploited a unique feature of trypanosomes to...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Fritz, Melanie, Vanselow, Jens, Sauer, Nadja, Lamer, Stephanie, Goos, Carina, Siegel, T. Nicolai, Subota, Ines, Schlosser, Andreas, Carrington, Mark, Kramer, Susanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652759/
https://ncbi.nlm.nih.gov/pubmed/26187993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv731
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