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Complex long-distance effects of mutations that confer linezolid resistance in the large ribosomal subunit
The emergence of multidrug-resistant pathogens will make current antibiotics ineffective. For linezolid, a member of the novel oxazolidinone class of antibiotics, 10 nucleotide mutations in the ribosome have been described conferring resistance. Hypotheses for how these mutations affect antibiotics...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652758/ https://ncbi.nlm.nih.gov/pubmed/26202966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv729 |
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