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The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success

Ischemic stroke remains a leading cause of morbidity and death for which few therapeutic options are available. The development of neuroprotective agents, a once promising field of investigation, has failed to translate from bench to bedside successfully. This work reviews the ischemic cascade, agen...

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Detalles Bibliográficos
Publicado en:J Neurosurg
Autores principales: Turner, Ryan C., Dodson, Sean C., Rosen, Charles L., Huber, Jason D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652647/
https://ncbi.nlm.nih.gov/pubmed/23331000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2012.11.JNS12408
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