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Heat shock protein 90 targeting therapy: state of the art and future perspective
Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone that plays a role in stabilizing and activating more than 200 client proteins. It is required for the stability and function of numerous oncogenic signaling proteins that determine the hallmarks of cancer. Since the initial discov...
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| Udgivet i: | EXCLI J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Leibniz Research Centre for Working Environment and Human Factors
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652636/ https://ncbi.nlm.nih.gov/pubmed/26600741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2014-586 |
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